minute details within thick specimens with perfect clarity
in patch-clamp experiments
The ECLIPSE FN1?developed especially for electrophysiological
research?features enhanced operability in every aspect to
facilitate patch-clamp experiments. Advantages offered by
the FN1 include slim body, streamlined structure, improved
electrode placement, long working distance, and greater noise
reduction. A deeper area of the specimen can be observed clearly
with IR light. The innovative motorized Multi Patch System
allows multipoint patch-clamp experiments to be conducted
accurately and easily, greatly enhancing the efficiency of
|Automated Multi Patch System
Multi Patch System can be easily added to the FN1 to motorize
field of view and magnification adjustment operations. With
the addition of dedicated motorized manipulators, electrodes
can be automatically moved to pre-selected cells of interest
in multiple fields of view without moving the objective or
|Viewfield is moved by swinging
the optical path.
||Electrode moves in conjunction
with changes in viewfield.
|One lens covers from low to
The newly developed high NA, long working distance 16x objective
(NA 0.8, W.D. 3.0) provides 5.6x, 16x, 32x and 64x magnifications
when combined with an optional magnification module. This
objective enables observation from a low magnification widefield
of up to 2.0mm to a high magnification high resolution field
without changing objectives.
|Image deeper areas with
ultimate clarity with IR-DIC
Axial chromatic aberration in near-infrared region (up to
850nm) has been corrected in 40x and 60x objectives to clearly
observe the minute structure of a thick specimen. The 100x
objective (NA 1.1, W.D. 2.5) is the world¡¯s first water dipping
lens with depth-induced aberration correction. Because of
its special correction ring, this lens can correct spherical
aberration induced by imaging deep in tissue or by working
at physiological temperatures. Consequently, it is ideal for
IR-DIC imaging and confocal applications as well as Multi-Photon
imaging. Alternating the wavelength from visible to infrared
or the illumination technique from DIC to Oblique Light is
carried out simply by rotating the condenser turrets.
Access of microelectrodes to the specimen is easy as the objectives
have a long W.D. of 2.5-3.5mm and broad approach angle up
easy objective changeover
Objectives mounted on the sliding nosepiece can be raised
when switching magnifications. This prevents the objective
from colliding with the manipulator or the chamber. The retraction
distance is 15mm, so even a thick glass dish is protected.
The lens top can be easily dipped (approximately 1mm) into
the bath solution by using the lever to eliminate the risk
of specimen disturbance.
within your reach
The focus knob and field diaphragm ring are located on the
front part of the microscope base, and there are no cumbersome
outside belts; so operation is easy when using a fixed stage.
An optional remote handle is also available to enable operation
from outside the cage.
Electrical noise has been successfully reduced by utilizing
fiber illumination to bring light into the system from outside
the cage and by connecting ground pins to all main parts of
the microscope. Vibration noise has also been reduced by undertaking
critical measurement and simulation analysis to improve microscope
to a broad range of experimental needs
By inserting a spacer between the body and the arm, you can
raise the microscope height 10-30mm. This facilitates large
specimen observation. Moreover, the condenser, sub-stage and
turret can be removed entirely from the microscope to allow
for more free space, depending on the purpose of the experiments.