Innovative motorized laser TIRF system
Newly developed motorized laser TIRF illumination unit allows laser incident angle adjustment, shutter control and switching to widefield fluorescence excitation with the control pad or NIS-Elements software. The laser incident angle can be stored with a single touch of the control pad button. Stored laser incident angles can be easily reproduced. This enables alternate time-lapse recording between fluorescence and multi-wavelength TIRF images.
Ultra-high signal/noise ratio enables observations of single molecules
The extremely high S/N ratio created by Nikon's laser TIRF imaging system makes it possible to observe single molecules. Thanks to Nikon's proprietary Noise Terminator mechanism, the system can also produce breathtaking epi-fluorescence images with a high S/N ratio.
Fluorescent receptor images
Specimen: YFP-tagged neurotransmitter receptors expressed in dispersed hippocampal neurons in primary culture
Images courtesy of : Dr. Chieko Nakada, Kyoto University, Co-researcher: Professor Shigeo Okabe, Tokyo Medical and Dental University
* Bright images up to the edge of the view field are obtained.
* High-performance fluorescence cassette holder eliminates the possibility of registration shift in the optical axis for each laser wavelength.
* Simultaneous mounting of other modules such as laser tweezers is possible thanks to the expandable stratum structure of the Ti series microscope.